Challenge for Treatment of Unresectable Pancreatic Cancer
نویسندگان
چکیده
Patients with pancreatic cancer have an especially poor prognosis, with a 5-year survival rate of < 1% and a median survival of 4-6 months. The management of patients with pancreatic cancer depends on the extent of the disease at diagnosis. However, at the time of diagnosis the vast majority of pancreatic cancers are at an advanced disease state, and surgical resection with curative intent is indicated in less than 10% of such patients [1, 2]. Unfortunately, a cure for pancreatic cancer is still elusive and current opportunistic screening strategies are not yet effective. In 2007, we planned a study for an early detection of pancreatic cancer using image diagnosis. The study was to compare Diffusion-Weighted magnetic resonance Imaging (DWI) and Multi Detector-Row Computed Tomography (MDCT) for detection of primary pancreatic cancer. By reviewing the images of patients at high risk for pancreatic cancer with Main Pancreatic Duct (MPD) dilatation was shown by Magnetic Resonance Cholangio Pancreatography (MRCP). We concluded performance of DWI and MDCT that was equivocal for detection of pancreatic cancer in a high risk population with MPD dilatation. The combination of MRCP and DWI for detection of pancreatic cancer allowed the identification of a high-risk population and tumor detection with a single imaging modality without any need for contrast medium [3].
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تاریخ انتشار 2014